British Journal of Pharmacology (Free subscription) | 18/09/2008
Expression of transgenes in midbrain dopamine neurons using the tyrosine hydroxylase promoter Gene Therapy advance online publication, September 18, 2008. doi:10.1038/gt.2008.148 Authors: M S Oh, S J Hong, Y Huh & K-S Kim
British Journal of Pharmacology (Free subscription) | 11/09/2008
Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells Gene Therapy advance online publication, September 11, 2008. doi:10.1038/gt.2008.143 Authors: B Moreno-Carranza, M Gentsch, S Stein, A Schambach, G Santilli, E Rudolf, M F Ryser, S Haria, A J Thrasher, C Baum, S Brenner & M Grez
British Journal of Pharmacology (Free subscription) | 08/09/2008
Viral vectors: from virology to transgene expression British Journal of Pharmacology advance online publication, September 8, 2008. doi:10.1038/bjp.2008.349 Authors: D Bouard, N Alazard-Dany & F-L Cosset
Reportergene (Free subscription) | 01/09/2008
Of course, a critical drawback of inducible transgene expression is the amount of basal expression (leakage) responsible to making noise in the discrimination of specific transgene patterns analysis (and even, to reduce potentially harmful effects of transgene). The Australian team of from Stuart M Pitson (University of Adelaide) by incorporating AU-rich mRNA destabilizing elements...
British Journal of Pharmacology (Free subscription) | 26/08/2008
Stable Transgene Expression From HSV Amplicon Vectors in the Brain: Potential Involvement of Immunoregulatory Signals Molecular Therapy advance online publication, August 26, 2008. doi:10.1038/mt.2008.175 Authors: Masataka Suzuki, E. Antonio Chiocca & Yoshinaga Saeki
British Journal of Pharmacology (Free subscription) | 26/08/2008
Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum Molecular Therapy advance online publication, August 26, 2008. doi:10.1038/mt.2008.170 Authors: Christopher D Herzog, Biplob Dass, Mehdi Gasmi, Roy Bakay, James E Stansell, Mark Tuszynski, Krystof Bankiewicz, Er-Yun Chen, Yaping Chu, Kathie Bishop, Jeffrey H Kordower & Raymond...
Physorg (Free subscription) | 22/09/2008
A study by scientists from the Nairobi-headquartered international research centre icipe, in collaboration with the French Institut de Recherche pour le Développement (IRD) has established that bees have the potential to mediate the escape of transgenes (genetically engineered material) from crops to their wild relatives over several kilometres. The findings, which have been published in the...
Science Daily (Free subscription) | 22/09/2008
Bees have the potential to mediate the escape of transgenes (genetically engineered material) from crops to their wild relatives over several kilometers. The findings bear significant implications for the introduction of genetically modified crops in Africa.
Red Orbit (Free subscription) | 17/09/2008
... gene targets, the CompoZr ZFN platform will eventually include ZFN-based kits for targeted transgene insertion and a catalog of off-the-shelf reagents for commonly studied gene targets, gene families, and pathways. Applications for Sigma's new platform technology include creation of knockout and knock-in cell lines, cell lines that yield significantly greater amounts of protein, and novel...
PR News Wire (Free subscription) | 16/09/2008
... gene targets, the CompoZr ZFN platform will eventually include ZFN-based kits for targeted transgene insertion and a catalog of off-the-shelf reagents for commonly studied gene targets, gene families, and pathways. Applications for Sigma's new platform technology include creation of knockout and knock-in cell lines, cell lines that yield significantly greater amounts of protein, and novel...
Business Wire (Free subscription) | 04/09/2008
... Drugs Limited (SCDL) - Sudershan Biotech Limited - Themis Medicare Ltd - Titan Biotech Limited - Transgene Biotek Limited - Unichem Laboratories Ltd. - USV India Ltd. - Varda Biotech (P) Ltd. - Venus Remedies - VHB Life Sciences Inc. - Vins Bioproducts Limited - Virchow Biotech (P) Ltd. (VBPL) - Viswagen Biotech Pvt. Ltd. - Wockhardt Biopharmaceuticals - Yashraj Biotechnology Limited - Zenotech...
Ouroboros (Free subscription) | 28/08/2008
Across species, a common symptom of advanced age is loss of brain function. Aging negatively affects a broad range of neural activity, including learning (reflected in long-term potentiation), control of motor function, and memory. Wouldn’t it be nice if we could slow that process down, or halt it altogether? A group at Kyushu University has managed to do just that. By introducing a transgene...
