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Complete Genomics Service Targets $1000 Genome by Spring 2009

Bio-IT World | Complete Genomics emerged from stealth mode today brandishing an audacious service model for wholesale next-generation sequencing, with its first human genome already assembled and the CEO’s pledge to reach the magical “$1000 genome” price point as early as spring 2009.

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DNA Nanoballs, Petabytes of Data Mark Complete Genomics Platform

Bio-IT World | With the unveiling today of the next phase of the next-generation sequencing era by Complete Genomics comes intense scrutiny of the sequencing-by-hybridization strategy that the company says will deliver one million genome sequences in the next five years

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Will Genetic Engineering Ruin Sports?

I will have to begin in mentioning that I am not a sports nut. I do like to watch the occasional baseball and football game. Despite this, the topic of sports is going to be may main topic. But not just sports in curiosity who will win the next Superbowl, but sports in concern with genetics. Where will the idea of sports go with the introduction (and advancement) of genetic engineering? Will such technology,...

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Will genetic testing motivate you to healthier life?

With genetic testing companies sprouting everywhere, people now have the resource to know their risks for certain types of disease. Companies like Navigenics, 23andme Inc. and DeCode Genetics all offer genetic tests to their consumers to show whether certain genetic mutations make them more likely to develop diseases such as heart disease, cancer or diabetes. [...]

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Information theory and mutual information between genetic loci

The International HapMap is a massive project to determine the genotypes for up to 3 million single nucleotide polymorphisms (SNPs) in samples of people from 11 population samples around the world. The current data release ( Phase 3 includes genotypes for a subset of over 1.5 million SNPs in 1,115 people. The 11 population samples include people of African ancestry from the US Southwest, Utah residents...

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Discarding Our “Aging-Blinders”

This is a long, but important, post... This term at Queen’s I am teaching my favourite undergraduate course entitled “Genetics and Justice”. This course examines the ethical, social and legal implications of the genetic revolution. And yesterday the class had a spirited debate and discussion on the aspiration to retard (and even eliminate) senescence. To set the context for the class, we first watched...

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Your Genome -- for Five Thousand Dollars?

Starting next spring, a complete human-genome sequence can be ordered for $5,000 through a new service announced by Mountain View, California startup Complete Genomics. This stunning price drop (sequencing currently costs about 20 times that amount) could completely change the way that human genomics research is done, and open up new possibilities in personalized medicine. A $5,000 genome would enable...

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THE RNA TIE CLUB AND LESSONS TO BE LEARNED IN HOW TO WIN A NOBEL PRIZE

- FROM THE ARCHIVE - (It’s Nobel season! Please enjoy a few from our archive on this topic) As of November 2005, 776 Nobel Prizes have been awarded (758 to individuals, 18 to organizations) in physics, chemistry, medicine, literature, peace, and economics. In that same month, according to the U.S. Bureau of Census, there were an [...]

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Scientists identify gene that may make humans more vulnerable to pulmonary tuberculosis

Researchers from the Genome Institute of Singapore (GIS) and its collaborators have now identified for the first time a new gene that may confer susceptibility to pulmonary tuberculosis. Their findings, published October 10 in the open access journal PLoS Genetics, reported that a gene named Toll-like receptor 8 (TLR8), previously shown only to recognize some [...]

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El Dorado High School students to study resources

More than 250 elementary and middle school students are expected to take part in a natural resources field day Oct. 17 at the Institute of Forest Genetics in Placerville.

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Postdoc wanted: Genomics & proteomics of yeast aging

My former collaborator, Professor Hao Li of UCSF’s Department of Biopharmaceutical Sciences, is looking for a postdoc to lead a project on “genomic approaches to understanding the mechanisms of aging,” using yeast as the model organism. Candidates should have an interest in genomics and training in yeast as an experimental system. The project will involve [...]

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Sunspots 180

Things I have recently spotted that may be of interest to someone else: Humor: A hilarious video (non-political, in any sense I can think of) of a Southern pastor, telling a PG or G rated story about a husband and wife with some zipper problems . Science: Carl Zimmer on the genetics of human intelligence , published in Scientific American . Bottom line: no genes with major effects on intelligence have...

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Metabolomics: Biochemistry's New Look

Until now, metabolomics researchers have had to adapt technology developed mainly for proteomics. But there are now solutions designed with them in mind. (...) Metabolomics - the comprehensive study of metabolic reactions - is gaining ground alongside its older siblings genomics and proteomics. "Unlike some of the other 'omics' that we have seen, metabolomics is going to produce a lot of useful...

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DNA Could Reveal Your Surname

Dr King said: "In Britain, surnames are passed down from father to son. A piece of our DNA, the Y chromosome, is the one part of our genetic material that confers maleness and is passed, like surnames, from father to son. Therefore, a link could exist between a man's surname and the type of Y chromosome he carries. A simple link between name and Y chromosome could in principle connect all men... PhysOrg.com...

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15 Answers to Creationist Nonsense

When Charles Darwin introduced the theory of evolution through natural selection 143 years ago, the scientists of the day argued over it fiercely, but the massing evidence from paleontology, genetics, zoology, molecular biology and other fields gradually established evolution’s truth beyond reasonable doubt. Today that battle has been won everywhere–except in the public imagination. Embarrassingly,...