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Frost & Sullivan Recognizes Exiqon for Growth Strategy Leadership in the Cancer Molecular Diagnostics Market

PALO ALTO, Calif.--(BUSINESS WIRE)--Based on its recent analysis of the U.S. cancer molecular diagnostics market, Frost & Sullivan recognizes Exiqon A/S with the 2008 North

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Cancer Molecular Diagnostics: On The Critical Path To Personalized Medicine

The Healthcare practice at Frost & Sullivan is pleased to announce its 2008 Quarterly Analyst Briefing Presentation on the North American cancer molecular diagnostics market to be held on Thursday July 24, 2008 at 10:00 a.m. PDT. The presentation will cover strategic insight into the U.S.

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Advances in High-capacity Extrachromosomal Vector Technology: Episomal Maintenance, Vector Delivery, and Transgene Expression

Advances in High-capacity Extrachromosomal Vector Technology: Episomal Maintenance, Vector Delivery, and Transgene Expression Molecular Therapy advance online publication, July 15, 2008. doi:10.1038/mt.2008.156 Authors: Michele MP Lufino, Pauline AH Edser & Richard Wade-Martins

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Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses

Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses Molecular Therapy advance online publication, July 22, 2008. doi:10.1038/mt.2008.155 Authors: Akihiro Otsuki, Ankita Patel, Kazue Kasai, Masataka Suzuki, Kazuhiko Kurozumi, E Antonio Chiocca & Yoshinaga Saeki

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The Targeted Oncolytic Poxvirus JX-594 Demonstrates Antitumoral, Antivascular, and Anti-HBV Activities in Patients With Hepatocellular Carcinoma

The Targeted Oncolytic Poxvirus JX-594 Demonstrates Antitumoral, Antivascular, and Anti-HBV Activities in Patients With Hepatocellular Carcinoma Molecular Therapy advance online publication, July 15, 2008. doi:10.1038/mt.2008.143 Authors: Ta-Chiang Liu, Taeho Hwang, Byeong-Ho Park, John Bell & David H Kirn

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Acid Sphingomyelinase Overexpression Enhances the Antineoplastic Effects of Irradiation In Vitro and In Vivo

Acid Sphingomyelinase Overexpression Enhances the Antineoplastic Effects of Irradiation In Vitro and In Vivo Molecular Therapy advance online publication, July 15, 2008. doi:10.1038/mt.2008.145 Authors: Eric L Smith & Edward H Schuchman

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Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats

Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats Molecular Therapy advance online publication, July 15, 2008. doi:10.1038/mt.2008.146 Authors: Melissa K McCoy, Kelly A Ruhn, Terina N Martinez, Fiona E McAlpine, Armin Blesch & Malú G Tansey

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RNA Interference Screen to Identify Pathways That Enhance or Reduce Nonviral Gene Transfer During Lipofection

RNA Interference Screen to Identify Pathways That Enhance or Reduce Nonviral Gene Transfer During Lipofection Molecular Therapy advance online publication, July 15, 2008. doi:10.1038/mt.2008.147 Authors: Gregory A Barker & Scott L Diamond

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CombiMatrix's Newly Updated Autism Test Gains Market Attention

MUKILTEO, Wash., July 22, 2008 (PRIME NEWSWIRE) -- CombiMatrix Corporation (Nasdaq:CBMX) announced today that it has launched an updated version of its ATScan(tm) test for pre-disposition screening for autism, through its wholly owned subsidiary CombiMatrix Molecular Diagnostics (CMDX).

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Autism pre-birth gene test. Here?

Has the day finally come ? CombiMatrix Corporation (Nasdaq:CBMX) announced today that it has launched an updated version of its ATScan™ test for pre-disposition screening for autism, through its wholly owned subsidiary CombiMatrix Molecular Diagnostics (CMDX). The ATScan test has been…

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Cancer Molecular Diagnostics: On the Critical Path to Personalized Medicine

PALO ALTO, Calif.--(BUSINESS WIRE)--The Healthcare practice at Frost & Sullivan is pleased to announce its 2008 Quarterly Analyst Briefing Presentation on the North American

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Transcriptomics: Digging deep with RNA-Seq

The emerging view of eukaryotic transcriptomes is complex, involving overlapping transcripts, transcribed intergenic regions and abundant non-coding RNAs. A recently developed method — known as RNA-Seq — that uses high-throughput sequencing promises a more comprehensive understanding of this complexity.RNA-Seq involves direct sequencing of cDNAs

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Development: Ticking off new segments

Each vertebrate species has a characteristic number of segments along the body axis — humans have only 33 whereas snakes can have over 300 (see image). What developmental genetic principles lie behind these precise species-specific numbers? A paper that compares the molecular details of segment

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Human disease: Keeping risk in the family

In most cases, the disease risks associated with alleles identified in a genome-wide association study (GWAS) are too small to be useful to genetic counsellors. However, for relatives of affected individuals the risks are larger, and a new study introduces a statistic for quantifying this

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Epigenetics: Getting to the roots of mammalian imprinting

A recent study has identified a complex imprinting mechanism that has been conserved for over 148 million years in therian mammals, which include placental mammals and marsupials. These findings suggest that, contrary to previous theories, imprinting by germline-derived methylation evolved before the advent of therian