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Initiatives Seek To Raise Prostate Cancer Awareness Among Black Men, Improve Health Outcomes, Encourage Cardiovascular Exercise Among Minorities

The following summarizes recent efforts and initiatives that seek to reduce racial health disparities. Charles County, Md.: Ministers Alliance of Charles County and Vicinity; local health officials; Claudia Baquet, a doctor and specialist in health disparities at the University of Maryland School of Medicine; and state Sen.

1Vote!

Inhibiting 2 Pathways Rather Than 1 Enhances Anti-Tumor Effects

Two independent research groups have found that simultaneous inhibition of two signaling pathways resulted in substantially enhanced antitumor effects in mouse models of prostate and breast cancer. In an accompany commentary, Steven Grant, at Virginia Commonwealth University Health Science Center, Richmond, discusses the clinical importance of these studies and highlights some of the questions that...

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Men Age 75 And Older Should Not Be Screened For Prostate Cancer

Men age 75 and older should not be screened for prostate cancer, and younger men should discuss the benefits and harms of the prostate-specific antigen (PSA) test with their clinicians before being tested, according to a new recommendation from the U.S. Preventive Services Task Force. The recommendation and accompanying evidence summary appear in the August 5 issue of the Annals of Internal Medicine....

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New Gene Combination May Cause Deadly Prostate Cancer

Scientists at The Institute of Cancer Research have found that the partnering of two genes could be responsible for up to 600 British men developing a drug resistant and potentially deadly form of prostate cancer each year. The international study, published in the British Journal of Cancer, also outlines the discovery of a new prostate cancer gene, ACSL3.

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Possible Link Found Between X-rays And Prostate Cancer

Researchers at The University of Nottingham have shown an association between certain past diagnostic radiation procedures and an increased risk of young-onset prostate cancer - a rare form of prostate cancer which affects about 10 per cent of all men diagnosed with the disease.

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The Ratio Of Serum Testosterone To Prostate Specific Antigen Predicts Prostate Cancer In Hypogonadal Men

ORLANDO, FL (UroToday.com) - Dr. Abraham Morgentaler and colleagues examined the relationship between testosterone (T) levels and PSA in hypogonadal men. 184 patients with symptomatic hypogonadism (T

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Teaching And Mentoring: A Multi-Center Laparoscopic Radical Prostatectomy Experience

ORLANDO, FL (UroToday.com) - Canadian investigators created a teaching and mentoring method called "block" surgery to simplify and improve time efficiency and safety while maintaining acceptable oncological and functional outcomes during the learning curve of a laparoscopic radical prostatectomy (LRP). The LRP was broken down into 10 key "blocks" assigned different levels of difficulty. Practicing...

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Prostate Cancer Screening Must Be Continued To Be Effective

ORLANDO, FL (UroToday.com) - The AUA and American Cancer Society advocate offering men annual screening with serum PSA and DRE starting at age 50 years in the general population and earlier in high-risk men. In studies to examine whether lung cancer screening is beneficial, an important feature of using CT screening was that the screening regimen must be strictly adhered to in order to detect important...

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Patients With Prior TURP Undergoing Robotic Assisted Laparoscopic Radical Prostatectomy Have Higher Positive Surgical Margin Rates

ORLANDO, FL (UroToday.com) - With the incidence of robotic-assisted radical prostatectomy (RALP) increasing, questions regarding the significance of margin status have arisen. Patients with a history of a prior transurethral resection of the prostate (TURP), may have a higher incidence of positive margins because of the prior surgery.

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Does The Training Level Of The First Assistant Have An Impact On Blood Loss In Radical Prostatectomies?

ORLANDO, FL (UroToday.com) - Blood loss in radical prostatectomies has been an issue for a long time. New operative techniques led to an optimization regarding not only nerve sparing but also blood sparing attempts. These investigators prospectively studied the influence of the training level of the assisting doctor regarding blood loss in radical prostatectomies. 364 patients underwent radical prostatectomy...

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Does BMI Impact PSA Concentration By Variation In Plasma Volume?

ORLANDO, FL (UroToday.com) - Recent reports suggest that men with higher BMI have lower PSA concentrations due to dilution of a set PSA amount by a larger plasma volume. The study published in JAMA in November of 2007, drew such conclusion from a cohort of men that had a known diagnosis of prostate cancer (and went on to prostatectomy). The current report by Grubb and colleagues substantiates the findings...

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Transrectal High Intensity Focused Ultrasound In The Treatment Of Localized Prostate Cancer - The First UK Series

ORLANDO, FL (UroToday.com) - The use of HIFU in localized prostate cancer (PCa) is an emerging minimally-invasive technology that offers the potential fewer side-effects and effective cancer control. Visually-directed HIFU for the conduct of therapy for the Sonablate®500 device allows the user to change energy levels per pulse based on real-time greyscale ultrasound feedback.

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Prostate Cancer Genes Altered By Intensive Diet And Lifestyle Changes

The findings of a US pilot study on men with low risk prostate cancer suggests that following an intensive healthy diet and lifestyle regime emphasizing low meat and high vegetable and fruit intake, regular exercise, yoga stretching, meditation and support group participation, can change the way that genes behave and alter the progress of cancer, for instance by switching on tumor killers and turning...

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Correlation Between Length Of Positive Surgical Margins And Biochemical Recurrence After Radical Prostatectomy For Prostate Cancer

ORLANDO, FL (UroToday.com) - The presence of positive surgical margins in a radical prostatectomy (RP) specimen is an important negative prognostic factor, although the length of the positive margins was not an independent predictive factor for biochemical recurrence (BCR) in most studies. The aim of this study is to correlate the length and the Gleason grade of the positive resection margin with BCR...

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Benign Prostatic Hyperplasia - Nymox Starts Phase 3 Program For NX-1207

Nymox Pharmaceutical Corporation (NASDAQ: NYMX) announced that, following recent communications with the U.S. Food and Drug Administration (FDA), the Company is commencing its Phase 3 development program for NX-1207, Nymox's investigational product for the treatment of benign prostatic hyperplasia (BPH). The Company will begin Phase 3 clinical trials in the U.S. later this year to support a New Drug...