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Shots in the Dark: The Wayward Search for an AIDS Vaccine

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  1. 2. AIDS Vaccine Development: Challenges and Opportunities
  2. 3. Shots in the Dark: The Wayward Search for the AIDS Vaccine

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3Vote!

Cold virus may have caused 2007 AIDS vaccine trial failure

One of the biggest disappointments in AIDS research was the failure of Merck & Co.'s STEP trial of an experimental AIDS vaccine, which was terminated prematurely in 2007 when it became apparent that the vaccine seemed to increase the number...

+Vote!

50 best inventions of 09

What does a $10 Million Lightbulb , The AIDS Vaccine and The 3-D Camera all have in common? They were all hatched in 2009! Despite all sorts of economic turmoils , The year 2009 had also some success stories. A comparatively more positive year 2009 has been to last year interms of both recovery and discovery, [...]

3Vote!

Political leaders tour Providence "knowledge district"

By Philip Marcelo PROVIDENCE, R.I. -- U.S. Rep. David Obey , a Wisconsin Democrat and chairman of the House Appropriations Committee, joined Rep. Patrick Kennedy , Governor Donald L. Carcieri , Mayor David N. Cicilline and other state political leaders Friday morning on a tour of four biotech research facilities in Providence's Jewelry District. Kennedy said the two-hour tour was a pitch to garner...

3Vote!

Video Game Sales Fall 18%

Non-PC gaming sales in the U.S. totalled just $1.03 billion in October, down 19% from a year ago, NPD reports. Console sales were hit even harder, dropping 23% to $380.74 million. Here's how the units break out per console: Nintendo's (NTDOY) Wii sold 506,900 units, up 10% from September, thanks to its price cut. It's still down 37% year over year. Nintendo DS sold 457,600 units, down 13% m/m, down...

4Vote!

News: Time hails Natal as invention of 2009

In company of teleportation, AIDS vaccine. Time.com has put forward Project Natal as one of The 50 Best Inventions of 2009. The online arm of the famous US magazine said traditional controllers have stood as a "barrier between gamers and total Tron-like immersion" since the invention of Pong. "This year Microsoft demonstrated a technology codenamed Project Natal that enables players...

3Vote!

AIDS Vaccine Beat Out By Xbox's Natal In Time's "Best Inventions of 2009"

Ending the worldwide AIDS epidemic would be awesome, but have you seen the demos of Microsoft's controller-free gaming system? Time Magazine released its list of the 50 best inventions of 2009 . The AIDS vaccine was good for 8th place, behind the tank-bred tuna (#2), the "smart thermostat" (#4), and, yes, Project Natal (#5). The top spot went to NASA's Ares 1 rocket, which could take man...

3Vote!

Time picks Natal as one of 2009's best inventions

Sitting on Time Magazine's 50 Best Inventions of 2009 amongst notables like the world's first AIDS vaccine (still in trials) and meat farms seems like an awkward place for Microsoft's Project Natal . But that's exactly where it resides, paired with glowing praise for its boundary-breaking implications. "Since time immemorial ... one barrier that has stood between gamers and total Tron-like immersion...

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3Vote!

Natal Wins Time Magazine Honors

Project Natal (X360) A better invention than the AIDS vaccine and teleportation, apparently.

3Vote!

Bill Gates’ Plan for Fixing the World

It’s been more than a year since Bill Gates stepped down from day-to-day operations at Microsoft to focus on his philanthropic efforts through the Gates Foundation . In that time, Gates has traveled the world (in the past week alone, he’s been in China, India, and today, New York), strategizing the best use of his enormous fortune and that of his foundation, which, also includes $31 billion...

5Vote!

Will Anyone in Their Right Mind Actually Buy Into These Three New Vaccines?

A storm has erupted over the announcement last month that an experimental AIDS vaccine tested in Thailand proved modestly effective. It was billed as a major scientific advance — the long-awaited hard evidence that it is possible to inoculate people against AIDS. But now the trial has been called into question in a way that is overblown and possibly destructive. But this isn’t the first...

3Vote!

The AIDS Vaccine May Not Be As Effective As First Thought

The latest analysis of the results of an AIDS vaccine clinical trial in Thailand suggests it may not have been as effective as researchers originally thought.

3Vote!

GSK, Pfizer launch new HIV drug venture

The joint venture between GlaxoSmithKline and Pfizer , Viiv, has officially opened up for business as a powerhouse developer of new HIV therapies. But analysts are wondering if Viiv has more to do with getting the two pharma giants out of the controversial therapeutic area than with ramping up new drugs for the lethal virus. "By being 100 per cent dedicated to HIV, we will reach more patients...

3Vote!

New AIDS Vaccine

The NIH is doing new studies on potential AIDS vaccines.

3Vote!

The Devil in Anna Eshoo’s Details

I can't tell you how happy I am to hear that Rep. Eshoo did not intend to put an evergreening period in her bill. Because not only would it apply to important breast cancer drugs, but also to drugs yet to be developed for everything from Alzheimers to an AIDS vaccine. Thank you, Rep. Eshoo, for your commitment to having a bill that does not allow for "evergreening." Now the question becomes...

3Vote!

Protection of Stem Cell-Derived Lymphocytes in a Primate AIDS Gene Therapy Model after In Vivo Selection

Background There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5Δ32) cells, setting the stage for transplantation of naturally resistant, or genetically modified stem cells as a viable therapy for AIDS. Hematopoietic stem cell (HSC)...