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HSP90 Inhibitor To Advance To Clinical Development - Prominent In Tumor Cells Where It Promotes Activity Of Proteins Controlling Growth And Survival

Exelixis, Inc. (Nasdaq:EXEL) announced today that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for XL888, a novel anticancer compound. XL888 is an orally available small molecule inhibitor of HSP90, which is a chaperone protein that promotes the activity and stability of a range of key regulatory proteins, including kinases.

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Exelixis Files IND Application for Cancer Drug

Exelixis, a development-stage biotechnology company, has submitted an investigational new drug application to the FDA for XL888, a novel anticancer compound.

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Exelixis Files IND Application for XL888

Exelixis, Inc. (Nasdaq:EXEL) announced today that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for XL888, a novel anticancer compound.

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Exelixis Announces October 6 Webcast of Presentation at the JMP Securities 3rd Annual Healthcare Focus Conference

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq:EXEL) announced today that George A. Scangos, PhD, President and Chief Executive Officer of Exelixis, will present at the

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Biotech Platforms

It is interesting to see the notion of tech platforms play out in other fields. Specifically, the biotech field is all abuzz on platforms. For example Exelixis' oncology platform built on kinase inhibitors.Having a validated drug discovery platform is the first and most important criterion for defining a good platform company. The platform is typically comprised of a combination of technology, experienced...

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Exelixis: A Platform Company for Oncology

Ohad Hammer submits: The pharmaceutical industry is in the midst of a severe innovation crisis, where more R&D money results in less approved drugs. In parallel, sales of most traditional blockbusters are being cannibalized by generic competition, forcing the big pharmas to exploit new concepts and rush new drug candidates to their pipelines. Nearly half of all drugs that are expected to enter the...

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Exelixis Announces September 3 Webcast of Presentation at the Thomas Weisel Partners 2008 Healthcare Conference

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq:EXEL) announced today that Frank Karbe, Executive Vice President and Chief Financial Officer of Exelixis, will present at

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Exelixis Inc. Q2 2008 Earnings Call Transcript

Exelixis Inc. (EXEL) Q2 2008 Earnings Call Complete Story »

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Exelixis Q2 loss widens to $45.1M

Exelixis Inc. on Tuesday reported a second quarter loss of $45.1 million, or 43 cents a share, compared to $28.6 million, or 29 cents a share for the same period last year. (EXEL)

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Exelixis Announces Second Quarter 2008 Financial Results

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq:EXEL) today reported financial results for the second quarter ended June 30, 2008.

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Exelixis Announces August 8 Webcast of Presentation at the Bank of America 2008 Specialty Pharmaceuticals Conference

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq:EXEL) announced today that George A. Scangos, PhD, President and Chief Executive Officer of Exelixis, will present at the

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Exelixis Notifies GlaxoSmithKline of Proof-of-Concept for XL184

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq:EXEL) today announced that it has notified GlaxoSmithKline (GSK) that it has achieved proof-of-concept for XL184 under

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Exelixis Announces August 5 Webcast of Its Second Quarter 2008 Financial Results and Business Update Conference Call

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq:EXEL) will release its second quarter 2008 financial results on Tuesday, August 5, 2008, after the markets close.

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Exelixis starts thyroid cancer treatment test

Exelixis Inc. started a late-stage clinical trial of a treatment for medullary thyroid cancer. (EXEL)